1. In addition, extracellular basophilic bodies were seen in portal spaces and sinusoids.

2. Subependymal layer and zona medialis are particularly densely vascularized by capillary sinusoids.

3. Decrease of the granulopoiesis, disintergration of the marrow sinusoids, and osteoporosis are the most important additional signs.

4. Bone marrow aspirate revealed all patients necrotic bone marrow particles with distended sinusoids and necrotic eosinophile material.

5. Anastomosing proliferation of capillary sized vessels, reminiscent of splenic sinusoids (Am J Surg Pathol 2010;34:942), within a framework of nonendothelial supporting cells Rare to absent mitotic activity Mild endothelial nuclear variability and scattered hobnailed endothelial cells …

6. The audiogram is usually obtained using a device called an Audiometer. A pure-tone Audiometer allows the practitioner to change the frequency of the sinusoid, change stimulus level (usually in 5-dB steps), route the sound to different transducers (earphone, maybe a bone vibrator, discussed later, or speakers), and to turn the signal on and off.